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The Philadelphia Phillies (23-11) will host the San Francisco Giants (15-19) in a primetime National League showdown on Sunday Night Baseball. The Phillies currently have the best record in the NL. Meanwhile, the Giants rank third in the NL West after losing four of their last five games. The Phillies are fourth in the league in RBI (158), while San Francisco ranks 22nd (120). 

First pitch is set for 7:10 p.m. ET. San Francisco is the -118 favorite (risk $118 to win $100) on the money line in the latest Giants vs. Phillies odds from SportsLine consensus, while the over/under for total runs scored is 7.5. Before making any Phillies vs. Giants picks, be sure to see the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 6 of the 2024 MLB season on a profitable 112-89 run on top-rated MLB picks dating back to last season, and it has excelled on top-rated run-line picks during that span, going 20-8 (+708). Anybody following has seen huge returns.

Now, the model has set its sights on Giants vs. Phillies and locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for Phillies vs. Giants:

  • Giants vs. Phillies money line: San Francisco -118, Philadelphia -102
  • Giants vs. Phillies run line: Philadelphia +1.5 (-171)
  • Giants vs. Phillies over/under: 7.5 runs
  • SF: The Giants are 4-11 in their last 15 games on the road
  • PHI: The Phillies are 8-0 in their past eight games at home
  • Giants vs. Phillies picks: See picks at SportsLine

Why you should back the Phillies

Bryce Harper is a powerful slugger who has the pop to push the ball anywhere on the diamond. Harper's swing is effortless but he can be aggressive as a batter. In 30 games, he's recorded six home runs, 18 RBI, and has an OPS of .820. In his last game, Harper was 1-of-3 with a single and two runs scored.

Catcher J.T. Realmuto has a good feel as both a hitter and defender. Realmuto will make consistent contact at the dish due to his strong hands. Behind the plate, he can call a solid game and throw runners out. He's hitting .241 with five home runs and 14 RBI. On April 28 versus the Padres, Realmuto went 2-of-5 with a homer and three RBI. See which team to pick here

Why you should back the Giants 

Second baseman Thairo Estrada gives the Giants some much-needed juice. Estrada has quick hands and the instincts to make the right read both offensively and defensively. The 28-year-old makes consistent contact while playing superb defense. He's batting .254 with four home runs and 17 RBI. In his last outing, Estrada went 3-of-5 with three base hits and one RBI.

Left fielder Michael Conforto provides San Francisco with a patient hitter at the plate. Conforto can spray the ball all over the field and has the power to hammer some long balls. This season, he's batting .250 with five home runs and 16 RBI. He's tallied a hit in nine of his last 12 games. In Saturday's loss, he was 1-of-4 with a single. See which team to pick here.

How to make Phillies vs. Giants picks

SportsLine's model is leaning Over on the total, projecting 9.2 combined runs. It also says one side of the money line has all the value. You can only get the model's MLB picks at SportsLine.

So who wins Giants vs. Phillies, and which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that's 112-89 on top-rated MLB picks, and find out.